No, Muslims worship God in heaven. The Khaba also known asal-Masjid al-Haram is the house of God on earth and it is the direction of prayer Muslims face when performing the obligatory prayer (Salah).
Bukhari, Volume 6, Book 60, Number 19:
Narrated Al-Bara:
We prayed along with the Prophet facing Jerusalem for sixteen or seventeen months. Then Allah ordered him to turn his face towards the Qibla (in Mecca):–
“And from whence-so-ever you start forth (for prayers) turn your face in the direction of (the Sacred Mosque of Mecca) Al-Masjid-ul Haram..” (2.149)
The Prophet Muhammad longed to face Mecca in prayer and God has seen his yearning.
Quran [1:144] We have certainly seen the turning of your face, [O Muhammad], toward the heaven, and We will surely turn you to a qiblah with which you will be pleased. So turn your face toward al-Masjid al-Haram. And wherever you [believers] are, turn your faces toward it [in prayer]. Indeed, those who have been given the Scripture well know that it is the truth from their Lord. And Allah is not unaware of what they do.